As the use of automobiles increases, people spend more time in the car, and the air quality inside the vehicle is receiving more and more attention. Due to the large use of organic chemical materials in automotive decorative materials, it is easy to produce a variety of toxic and harmful volatile compound gases, which would cause the odor inside the car to affect the health of the driver. The unique nano-porous structure of SiO2 aerogel gives it excellent adsorption properties. Therefore, in this paper, the concentrations of the CO, PM2.5 and TVOC under different road environments and driving conditions are detected and analyzed, based on the active purification technology related to SiO2 adsorption aerogel, and studies the in-car air odor dissipation control technology. The results show that the concentration of CO in each ventilation mode is higher in the congested road sections, and the road congestion is the main influencing factor of CO concentration in the vehicle; the PM2.5 concentration in the air of the vehicle is greatly affected by the air quality outside the vehicle, and the road condition and form status have no decisive influence on it; the TVOC concentration in the car is relatively stable when the window is closed, but in unobstructed road conditions, the TVOC concentration is lower than that in the congested road conditions and it presents a declining trend; in the air inside the vehicle, for the CO, TVOC and PM2.5 suspended particulate matters, etc., we can use active purification technology related to SiO2 adsorption aerogel to control and dissipate the odor and air pollutants in the vehicle effectively.