With the people’s living standards improving greatly, the demand for chemical food additives (CFA) has been continuously increasing. But in the backward CFA production system, there is lack of transparency for the processing information, making it difficult to gain the consumers’ trust. For this, this paper designs a complete set of automatic production lines for CFA to control and manage the whole process, and also designs the Internet of Things (IoT)-based electronic tag system. The research results show that the system can make distributed control of various dispersed input and output points in the CFA production process; the design of electronic tags can make it clear for the people about the information of raw materials entering factory, production and processing information, inventory information, and ex-factory information; the entire design system works well and can greatly improve the management efficiency of CFA manufacturers. This research lays a technical foundation for the technical upgrading of CFA production lines.