The purpose of this study is to understand the operation mode of computational fluid dynamics (CFD) parallel computing technology for non-equilibrium flow. To this end, this paper mainly studies the flow field of supersonic ramjet engine (Scramjet). Through simulation of various component equations, chemical non-equilibrium effects, turbulence equations and transport coefficients, etc., it also studies the CFD parallel calculation by simulating the flow field of the scramjet. Innovative insights were put forward for each aspect, and the three-dimensional massively parallel software platform AHL3D oriented to chemical non-equilibrium flow mainly used in the simulation of the flow field of the scramjet engine was developed. Finally, it realizes the multi-block parallel computing for docking grid, the misaligned splicing grid and the overset grid. This algorithm has better robustness, simple implementation, and also low computational complexity, high computational efficiency and high application value.