The purpose of this study is to strengthen the effect of whole process cost management (WPCM) in the Dangerous Chemical construction projects. To this end, this paper studies the WPCM control of Dangerous Chemical construction projects. Building Information Model (BIM) technology was introduced into Dangerous Chemical building, to analyse the application of BIM technology-based Dangerous Chemical construction project in all stages of WPCM management. The study found that the pipeline collision and rework phenomenon on the site are greatly reduced, the construction cost drops directly, and the cost change is reflected in time. Therefore, BIM Technology has changed the traditional ways of work. It can process the engineering information quickly and accurately. The application of BIM technology in the WPCM is conductive to achieving accurate, dynamic and real-time cost management.