This paper describes the use of a linear programming method to construct a formula for preparing culture medium for Spirulina platensis (S. platensis) algae using Vinh Hao natural mineral water (Binh Thuan Province, Vietnam) with a low cost. The results show that the cost of preparing the culture medium using Vinh Hao mineral water is less than 252.49 VND/L, which is approximately 13.05 % less than the cost of Zarrouk medium. To verify the optimised medium composition, S. platensis algae was cultured in the two media under the same conditions (25 to 40 C; pH 8.5 to 10.2). The algae biomass concentration reached 1.0 g/L after 7 d of culturing. The experimental growth rates of S. platensis algae in Vinh Hao culture medium and Zarrouk medium had an average difference of 1.49 %. This study provides a basis for implementing S. platensis algae production on an industrial scale using media formed from Vinh Hao natural mineral water from Binh Thuan Province, Vietnam.