A spinning disc reactor (SDR) is a useful equipment to produce monodisperse nanoparticles with controllable properties, as particle size and particle size distribution. Since the late 90s, this technology has been successfully proven for the reaction and solvent-antisolvent precipitation process. This paper reviews the works on the use of SDR to produce inorganic and organic compounds. Firstly, the more significant works on the subject are presented concerning the produced compound, then the factors influencing the process performances are examined in the light of the results in the literature. Finally, some considerations on the fluid stream's hydrodynamics modelling along the disc surface are attempted.