This work presents the analysis of Siberian Federal District regions major social-ecological-economic statistics based on research of the indicators of the Goal 7 “Ensuring Environmental Sustainability” of UN Millennium Development Goals (MDG). The results are analysed and discussed. Goal 7 contains three objectives and eight indicators. Energy intensity can be considered a key indicator of sustainability. The analysis of the social-economic development programs of the Siberian Federal District regions shows that most of the regions have not yet achieved the indicator levels of Goal 7, and the progress towards the goals is uneven. The regional authorities need to correct the programs of social-economic development in order to achieve the UN MDG goals. The comparison between Goal 7 indicators and goal progress results makes clear that the regions should pay more attention to the social-economic development directions as a basis for the development of the natural, economic and societal capital.