Bucaramanga is a city of more than 1 M inhabitants located in the northeastern region of Colombia. Currently, metropolitan area has problems related to utilization and elimination of plastic waste, which have increased due to the COVID-19 pandemic. This led to difficulties in plastic waste management, such as the low rate of rubbish and recycling collection activities and the increase of water, land, and air pollution; exposed at risk the ecosystems and the inhabitants of the region. The main objective of this work is to present a set of activities to respond to the increase in plastic waste related to COVID-19, through the development and implementation of a technology roadmap for Bucaramanga’s Metropolitan Area (BMA). It could enable environmental impacts minimization, through actions that will implement new technologies for conversion of plastic waste into energy in a short, medium, and long-term period.