Carbon neutrality is essential to limit global warming. The promotion of hydrogen cars in the transportation sector may be consistent with this policy. Hydrogen cars, because of their shorter charging time and longer operating distance per charge than electric vehicles, are suitable replacement for vehicles that emit air pollutants, such as large trucks. In this study, the basis for the Hydrogen Freight Vehicle (HFV) activation policy was prepared by quantitatively predicting the distribution trend and effect of HFV. The scenarios were classified based on the level of achievement of the Korean government's hydrogen vehicle supply targets. The survival curve was used to predict the number of HFV actually operating annually. In addition, routes with a high utilization ratio of HFV were predicted by dividing the traffic patterns of passenger and freight cars. In the future, routes with a high truck operation ratio would be identified and presented as areas that require intensive infrastructure expansion. Using the emission coefficients by vehicle type and speed, the reduction in air pollutants and the reduction in air pollution costs owing to the introduction of HFV was calculated. Our results predicted that 111,626 HFV may be operated based on the 2030 target. The proportion of HFV was high in the Goesan IC to Yeonpung IC section of the Jungbu Naeryuk Highway and it is expected that there will be more HFV in the future. As a result, the amount of air pollutants, CO2, Nox, CO, VOC, and PM2.5, CO2 saved could be 17,006.96 – 42,501.99 Mt by 2030. The cost-reduction benefits, of air pollution, increases to 89.7.11 billion KRW by 2030. The results of this study can be used as a basis for policy judgment when establishing and implementing policies to encourage the supply of HFV.