The aim was to carry out phytochemical screening of the extracts from various parts of the Swartzia latifolia plant, followed by the antimicrobial assay on the bacteria Staphylococcus aureus, Streptococcus mutans and Escherichia coli and yeast Candida albicans, soon after the antioxidant activity. Therefore, evaluations were started with a phytochemical survey of some parts of the plant, such as leaves, stem, stem bark, root and root bark, which indicated, qualitatively, the presence of tannins, flavonoids, triterpenoids and saponins. The root bark presented better results as the presence of the chemical groups mentioned above, as strong or very strong. In this way, the inhibition halos of the crude ethanolic and hexane extracts of the root bark against the bacteria and yeast were analyzed, where there was no inhibition on E. coli and C. albicans, but stronginhibition on S. aureus at concentrations of 20 and 30 mg L-1 in ethanolic (14 mm and 14 mm, respectively)and hexane extracts (19 and 15 mm, respectively) and S. mutans in the active ethanolic extract in 20 mg L-1 (9 mm) and 30 mg L-1 (11 mm), and active in the hexane extract 8 and 11 mm, in the same concentrations. For the antioxidant activity, it was only possible to verify the ethanolic extract of the root bark, which presented0.04 mg mL-1, while the BHT was 0.20 mg mL-1.