The purpose of this study is to realize the safe and reliable storage of hazardous chemicals. To this end, a real-time intelligent monitoring system for hazardous chemicals based on Internet of Things (IoT) technology was proposed and developed in this paper. The intelligent monitoring system is composed of the hazardous chemical information collection system, wireless transmission system and real-time monitoring system. The information collection system uses sensors to complete the collection of monitoring data, and then the collected data is reliably transmitted and exchanged through the wireless transmission system. Finally, the monitoring centre system can display the monitoring information of hazardous chemicals in real time, and conduct comprehensive analysis to classify the hazard level, make timely warning and alarm. Besides, the experiments were carried out on the function, performance, reliability, and environmental adaptability of the system. The experimental results show that the system can perform intelligent monitoring of the hazardous chemicals in real time and accurately so as to ensure the safe storage of hazardous chemicals.