In the liquid chemicals supply chain, due to the dangerousness and multiple chemical properties of liquid chemicals, its supply-chain finance (SCF) has certain particularity. There still exist the problems such as storage safety, warehouse financing and delivery transportation etc. over the whole supply chain. In this paper, a subjective and objective structure entropy method is used according to the entropy theory. Then, the gray relational analysis is introduced to assess the credit risk of financing enterprises facing liquid chemical supply chain finance, which enhances the integrity of the assessment. The result of research shows that the method can shorten the supply chain of liquid chemicals effectively and reduce the possibility of leakage and pollution of liquid chemicals.