As an organic waste with high nutrient contents, the conventional landfill or incineration of poultry waste has led to growing concerns. This study applies spatial analysis to two scenarios of poultry waste valorization supply chain design in New York State (NYS). Ultimately, the optimal distribution of slow and fast pyrolysis biorefineries within NYS based on the operational and economic parameters, locations of major poultry farms, crude refineries and corn croplands is discerned and mapped. Additionally, the biochar transportation costs are distributed in the form of heat maps. The outcome indicates that building a single centralized biorefinery in NYS for both slow pyrolysis and fast pyrolysis is more economically feasible than building multiple smaller biorefineries for ten slow pyrolysis and eight fast pyrolysis distributed biorefineries in NYS.