The objective of this research was to assess the reduction of imidacloprid and tebuconazole in soil plantations of Oryza sativa applying strains of Trichoderma spp. Regarding the methodology, 3 treatments were used; strain 1 (TS1), 2 (T163+TS1) and 3 (T163), 19 pots of 15 x 15 cm with 3.5 kg soil were used. One pot was used for the control group (without treatment) and eighteen pots were used for experimental groups (6 pots for each strain). 5 seeds Oryza sativa of Esperanza variety (MQR78) were planted in each pot on 2 cm to the soil surface, irrigation was carried out using drench technique every 24 hours for 90 days. For Trichoderma spp inoculation it was added 40 ml of strain 1, strain 2 and strain 3 in 18 pots with Oryza sativa seeds, identifying that the root measured 2 centimeters (6 pots for each strain). Likewise, the fungus strains were inoculated after 45 days to nourish the soil and a soil sample was taken after 45 days to identify the absorption of tebuconazole (fungicide) and imidacloprid (insecticide), finally the height of the plant (cm) was measured in each experimental strain, the plant was measured from the ground level to the tip of the longest leaf. The results showed that strain 1 reduced 12.39 mg / kg of imidacloprid and 17.31 mg / kg of tebuconazole. Regarding the percentage of decrease efficiency, it was concluded that strain 1 is more efficient with 64.2% for imidacloprid and 64.5% for tebuconazole and finally, strain 3 showed greater height of the Oryza sativa plant with 79.8 cm.